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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22772b2e252c7eea469c2ce21e159e6c5955db433327dbcd3a1c64ab84fd66bf' 
  AND token = 'z4s2+W61SrlLLvSpZMWKwweKSjN9Ujd2XqLzrd1A5TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}