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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cc79e7e965e7c2e933a96d1869002e66009bc5670ed75690ee69862c1380b09' 
  AND token = 'O5y2OmEEGXLLyh9aDvCLBs/ejeqBrAq9FHfZ2H7D33E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}