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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77682a9e647a445fda046e5b67a8efc080e59b72c20643d77ae2443aa69ef582' 
  AND token = 'm0CnApJBFUqwqOxe2CesPmsHbm+4dIXtzVzILZx5OL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}