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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e145a7b2ca4eee1251fa210865e0121ec93da68fade3c86e1b4d6f9c045c63' 
  AND token = 'oIH6LFPWyFYazetqwqbS4k8dQ4YxBKnTu2JD9PoLKek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}