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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4b6ba76056045f3f7e67a8398e646bf402b741927957e0ebc80d4c78512e36a' 
  AND token = 'IhmSV6Cc/cYTzRGjjST3sQ5Lgh1xZyI9x60uPf5fc7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}