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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ee560931cf37a0e642364408378e5e1fc811158398523a9021cf4da9a6d1cc' 
  AND token = 'vk1+PUX7Ugu2s0rkS42jJZgo4zPcrCOT8kumlIiT99Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}