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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a9a44b0f503a97f77f12bfdffdb12c0d190c147bcd02bfae0474dbf9a3d633' 
  AND token = '0esWyoV1ExeS6LbXLSOhAlUHE89S0DwVPPKLGMWmP5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}