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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527d3795940d7a8930cb9a5771887f1139457a963f632c89a98e8ad4d9ff6801' 
  AND token = 'Jp6GgrBLc+zhGh92S+okSkJTUdwypHP+A6kSJeODEvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}