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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65fc2b225cb89ae5f4384204845651b369b2574cf971eb7eb97263bb7cd71536' 
  AND token = '+WpZ8/NzYbEkP/59eX+5z7Qy/yfYh6RnQhakSeJtZCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}