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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac8d5928d9d40dcc96b76848506c5973eeb6acc0140b86d38522f9a521da0252' 
  AND token = 'PTSxAqUhX9hteNMudDbHjRCqsqCPEg/afB7nQrcq6lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}