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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301f30e287705f21d7f1c520513645f7d77f9125ae22681f92a4f3658d87f2d4' 
  AND token = '2RbKQ6ffyMVEmcfXceo0fMCA3YXo9HO9EM97b0tRpu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}