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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9b6efc1036331d62ef04175004ef87d2e2444730dfe828edf7f4bc7b41eb8e' 
  AND token = 'vbp+bob4SaqQv7vPR/LW4ILhnVsUe6vqYjCUxR8orv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}