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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4fad21410509f8ab34efe9f6bb3c764b3fb41f5d44a0145f9a797cfddaa503' 
  AND token = 'MOhhh+7YkqUja3LuNGbIoTe7tJahcXUhJK5/eajS8CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}