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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5de250ca11480a4e61932cc1b1473f38d742a195b41c5bc34cdfc1d378ff11' 
  AND token = 'IJ12isP04SncKQXpSIQqvCuOd6I0CIYyHZyr+Spa90c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}