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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4744952032c6ade4c04982d225d249eb488ed70f6c82224cc793bfeeca065ab8' 
  AND token = 'EIDomoTdNNoAvJUtWWIAS68ZAYlHAWpYj3PYcN3j9xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}