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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ad898509c50a3fca12fd7894a761ce1e50124662eced32ecf0ce2b0b5f499a1' 
  AND token = 'Q/4fuR9jtwmuIHr2PTepqKvQjEMfCIP+Gsf4fIfSftY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}