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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b26802724e5e6e750ea5bdc815fbe37df6c44815b9d7c70318dfcc5b92723c3' 
  AND token = 'N+kmBo/SKgM7748v6Re/iXqv4PYX38Ec1TTvyvKPcjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}