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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf6551bbe2f45dc22ff0991da27a977fd7d371ae6c594da2d4d6b488bb4a02d' 
  AND token = 'E2ir82pfMaM08/uao2TY6z2tphfYLK66lgb0D5k7Vk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}