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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448f29ed2f6d6c41853b30c4bc735805f130dd5b8ff5cb629761333948ac0300' 
  AND token = '83DaGQCu16xCCvYBzDCX+dvTeiqEDjdYVajtcTjpjc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}