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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b8f3fa0f5afaefb0adb2c93b2b8623e67124aefd194f6a7d52be918e002268' 
  AND token = 'yXXtlZIiTw8tFvbsG48uI2NVZ1KFMszy670wEk5QvbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}