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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4d553b49773d24be7e6dae25ea6ae76e05d23b9e0e5a96d7b6aac7b9a2edb8' 
  AND token = 'wp1EETkw4CZPbfZx9rv/KnLZSaXvhDSACZKqIMNZsss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}