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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76c896b7b62cbd744746ff058becdbb125400ff4d4bc1a2e75ca84fbaccd5078' 
  AND token = 'X/gIoPuQvIqF04+d+xGAB14jT4ZKOhG7sy4sjpQaHfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}