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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e60909eb59cfe89770957075fc2d5ffe1641c6bf9a52246738bddea67e86eb6f' 
  AND token = '9zxwUXVvp+yumCLczh+s4s7AS67EQt7kj0rlHlJ9cJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}