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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b927c49491f148c1d51360f686bd0febd883c0ee94d3d1e798a1146ca6274846' 
  AND token = 'G7AZXT9oZCT5x2uXYMwUFNncKpWsa+ErjVVWtG0kYT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}