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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9ad3c876c848b7a12753d4b56229b7a3274c0ebf0220d585272443cf9c1c14' 
  AND token = 'od1qRpIBOm1f+IeYXB0kiymPEfR+LkyxR2eeK7WPJVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}