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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '504f1da8f2cc7a8bb7ee8adad063904f2a2272285209e42ffd026780fef9a318' 
  AND token = 'e3Dr4t5Bk6YjOtd50pQGIOqHQW/dS4skvJHXPHrZbvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}