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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ac582f44b80dcb01da370cadc8562b2e7a49af39c459ad4fa67c025683da44' 
  AND token = '+F1BzsIoc4tWx6v/LxJ7UR1GeAWlvS8Lg5ggAlAaFF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}