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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a52ca0a9ab5f1bb05ae7d058f2ca4eb1d05858b4b89b341fe229e95b1a78cd' 
  AND token = 'zkB1piMdqo0A2koGr0aJYzhFdxKEpbVMQn6foTt134s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}