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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b186ff794ccf0446f2a0b3e0fb144ea535756d422dcb569c938678a4e6f0d6' 
  AND token = 'QdfDJjWrzxJlZn8+WSzySRP1/FzcH4W3jJBU34eEraA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}