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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8e6e9718f95ff009268e306804a719d6c0491b04e6ce3353ebc30648ec2f38' 
  AND token = 'HQMkas9oY3gcDorIRhKCJhbgb+ZlNvzqw6hB7t1Zsgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}