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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3777d2a1a3f50a6d7d0c6402975983d903de5d5143dab147b795952e1cac1380' 
  AND token = 'HSoGnlt3rvpn93VDpHfk5vhiVMBDC5e3mJJzAp2z4uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}