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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ffbbc3f230801b4e1f3deaa76fd48bd28ae792133aeb9fff342173c111d9f0' 
  AND token = 'S2DR6p4LNcwaVrRxTTDT1M03Ytsl+Og2b84cZlbTHQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}