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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45af36cddb45024257a55ca31bc7f8ab098fc84332c3fe73c9efb0b6c7433788' 
  AND token = 'nbayZevxE7xDw0FHEG2p8MckC6fxDrXmmx/KQRP2Zu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}