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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4415dcb002b706c59aa8cc6df1c8395249e93e29dbd9d3151c696e4bdf993652' 
  AND token = 'zE7/pK9TeczHxkZFGoZZPoh1/StyaDJFW8Bsq18sIJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}