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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72afd880dcb7feb67f304935e63ca5b7e5f86f2c8daae29cf1afd12dc2dfc70' 
  AND token = 'gJ2VvqM7sju0V/tSsJIWuBr6WrLzyKY4n618SSSnPTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}