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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87ced65a6f17df70e9cd53a9f860dfbc6a1bb7223c16557d7327299edb0ebd7c' 
  AND token = 'ud0I1SvW4VVMBw42B0qxNMdEmL8ey1hMrbG9GmVsR6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}