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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491b054d1102ca2de1bf5712643f47046aec881409e39ce583a6583a2a5eeebe' 
  AND token = 'Hr6IrJaEjc2G1pYeKPVhlGm1p/5z0dQ2t4mVPUtkAJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}