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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33da3a8d48f1b474d149b99d4f4155ff0b5d2638832cbef0866170b401af09a1' 
  AND token = 'JpWs08F1gCLJLES6RjBFsfs8oFmWqaFujDNje8gJYwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}