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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c0344a6e47a9a5cae5a4ed3e7b997e9d2491e83e2eb987948b83ec09003f6c' 
  AND token = '2QR3whkeH1c3/K+nc7jhO+XwhWSJsBcYpx0teZqEGOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}