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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '063fe3e90fe49455ad226f8185db6d1efea0ee6cc3d673699829f1b5ce3d1ebc' 
  AND token = '4qQqJ7Nr4Wd7S3zRneMBzz120pEoUjrx2e4Kz8/sU3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}