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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41f661a270a9e9877b9344af9bbf368e08d01d2ff2fbba37f8d904549062912' 
  AND token = 'GqmWiaKG+7Nj+VC/DhjhZRb7EP4DpldhSkyPk27iqcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}