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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd9f68e3190e665547dd723ceabdcb2e720e6e33d21b12f7d4498d3f64889d3c' 
  AND token = 'bcOpUC/p4l+0QNOi6+hWXyHeb2CmXaRS5UW0ocCCo3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}