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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e72f8766d15eca880b60223536fc3f0f3787af58d1691b01fbd0f2cb6c3d4988' 
  AND token = 'xg0tB5rcZM+BLn6wP8xeFpAcbq8aJAZCfSQLWTDgE5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}