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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea287abb0e4b0a9d112ac62be284505210d977fe9c8a9778b4564f1c2cfc740d' 
  AND token = 'xYV6ZX5Ay+m8d0m1NceCfEYFwXrw7jjZXc3tJnKcXPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}