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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db0cf990d17f5d76ebf0c1c1bf732516d4a836da24ac4b130ecd3b1dec10e8a2' 
  AND token = 'A4GZ2Lu50QVUtgEDHh3wcglKyBOk2OsC18h5Cmu2R34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}