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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fabed2b94e30ef503100c8b288efb9eff49ec7fb1274ce068074c0e3cf468df' 
  AND token = 'zrLHwXpJt1pgYTwN0VaqKsTWMPKF6VVhjUNfMb6b2As=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}