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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de18f7700f60c5b1d23b9ff002385d2049099783f850dea2c0217bd0cbb56a66' 
  AND token = 'za9LM4rsfXvZbLcJ0YlwLK+ShrCCW0bLjwAmJKN8ZfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}