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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '438da01f7f76654f6bd03d9765314545d3791f3f9f1b546d1a04cd686427de0b' 
  AND token = '1pYXE1bEXljkARVTK7UmlDn4EUWKr4x5DIlOYOLQO5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}