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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c225f4bd5001099f02bab3322f355ba37aad91217b8fe5a7408a8f184f705263' 
  AND token = 'a47b5J5p6V7hg2iB7DoqmUMoIdK9YOpv6sKCHLN9ORY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}