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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf9982e9549539fa25baee3bd7a6053da615e8d2129e5db23bdf52c34a7c6657' 
  AND token = '2OrWIsLe8SnSTXBmLOz37PoYZM629Vj6oU4j/OOLccs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}